Selank
Nootropic peptide for cognitive and anxiolytic research
Key Research Areas
Researched for anxiety reduction
Studied for cognitive enhancement
Investigated for neuroprotective effects
What is Selank?
Selank (TP-7) is a heptapeptide developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a synthetic analogue of the immunomodulatory peptide tuftsin, with an additional Pro-Gly-Pro sequence that increases its stability and enhances its neurotropic effects. Selank has been approved in Russia for the treatment of anxiety and is classified as a nootropic.
What It's Used For
Research applications include anxiety and stress response studies, cognitive function and memory enhancement research, neuroprotection investigations, immune modulation studies, and potential applications in depression and PTSD research. Selank is valued for its apparent lack of sedation and addiction potential compared to traditional anxiolytics.
How It Works (Mechanisms Explained)
Selank appears to work through multiple mechanisms. It modulates the expression of brain-derived neurotrophic factor (BDNF), which supports neuron health and plasticity. It influences the balance of neurotransmitters including serotonin, dopamine, and norepinephrine. Selank also affects the GABAergic system (though differently than benzodiazepines) and has immunomodulatory effects through its tuftsin-derived structure. This multi-faceted action may explain its combined anxiolytic and nootropic effects.
Common Research Stacks
Selank is sometimes studied alongside Semax (another Russian nootropic peptide) for complementary cognitive effects. It may also be researched in combination with other nootropics or adaptogens. Its immune-modulating properties make it interesting for combination studies with other health-promoting compounds.
Common Beginner Mistakes
Expecting immediate dramatic effects (cognitive benefits often develop gradually), not being consistent with administration (research protocols typically involve regular use), confusing it with benzodiazepines (different mechanism and safety profile), and improper intranasal administration technique (a common delivery method).
Reconstitution Basics
Selank is commonly available in both lyophilized powder form and pre-made nasal spray solutions. If reconstituting powder, use bacteriostatic water with standard sterile technique. For intranasal administration, specialized spray bottles are used. Refrigerate after reconstitution and use within 28 days. Intranasal delivery is popular due to direct access to the brain via the nasal mucosa.
Educational Disclaimer
This content is for educational purposes only and is not intended as medical advice. Research peptides are not approved for human use by regulatory bodies like the FDA. Always consult qualified healthcare professionals before making any health-related decisions.